Targeting glycan sulfation in a CD11c+ myeloid population inhibits early KRAS-mutant lung neoplasia()()()

Early lung carcinoma development may be modulated by innate host cellular mechanisms that promote tumor growth and invasion. We recently identified how a loss-of-function mutation in the glycan sulfating enzyme N-deacetylase/N-sulfotransferase-1 (Ndst1; involved in heparan sulfate biosynthesis) targ...

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Detalles Bibliográficos
Autores principales: Kim, So Young, Johns, Scott C., Gupta, Purva, Varki, Nissi, Fuster, Mark M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560828/
https://www.ncbi.nlm.nih.gov/pubmed/34715561
http://dx.doi.org/10.1016/j.neo.2021.09.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560828/
https://www.ncbi.nlm.nih.gov/pubmed/34715561
http://dx.doi.org/10.1016/j.neo.2021.09.008

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