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Multi-omics analysis identifies therapeutic vulnerabilities in triple-negative breast cancer subtypes

Triple-negative breast cancer (TNBC) is a collection of biologically diverse cancers characterized by distinct transcriptional patterns, biology, and immune composition. TNBCs subtypes include two basal-like (BL1, BL2), a mesenchymal (M) and a luminal androgen receptor (LAR) subtype. Through a compr...

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Detalles Bibliográficos
Autores principales: Lehmann, Brian D., Colaprico, Antonio, Silva, Tiago C., Chen, Jianjiao, An, Hanbing, Ban, Yuguang, Huang, Hanchen, Wang, Lily, James, Jamaal L., Balko, Justin M., Gonzalez-Ericsson, Paula I., Sanders, Melinda E., Zhang, Bing, Pietenpol, Jennifer A., Chen, X. Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560912/
https://www.ncbi.nlm.nih.gov/pubmed/34725325
http://dx.doi.org/10.1038/s41467-021-26502-6