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Single-cell RNA transcriptome landscape of hepatocytes and non-parenchymal cells in healthy and NAFLD mouse liver

Nonalcoholic fatty liver disease (NAFLD) is a global health-care problem with limited therapeutic options. To obtain a cellular resolution of pathogenesis, 82,168 single-cell transcriptomes (scRNA-seq) across different NAFLD stages were profiled, identifying hepatocytes and 12 other non-parenchymal...

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Detalles Bibliográficos
Autores principales: Su, Qi, Kim, Sun Y., Adewale, Funmi, Zhou, Ye, Aldler, Christina, Ni, Min, Wei, Yi, Burczynski, Michael E., Atwal, Gurinder S., Sleeman, Mark W., Murphy, Andrew J., Xin, Yurong, Cheng, Xiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560975/
https://www.ncbi.nlm.nih.gov/pubmed/34755088
http://dx.doi.org/10.1016/j.isci.2021.103233