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Velocity of myosin-based actin sliding depends on attachment and detachment kinetics and reaches a maximum when myosin-binding sites on actin saturate

Molecular motors such as kinesin and myosin often work in groups to generate the directed movements and forces critical for many biological processes. Although much is known about how individual motors generate force and movement, surprisingly, little is known about the mechanisms underlying the mac...

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Detalles Bibliográficos
Autores principales: Stewart, Travis J., Murthy, Vidya, Dugan, Sam P., Baker, Josh E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560993/
https://www.ncbi.nlm.nih.gov/pubmed/34508779
http://dx.doi.org/10.1016/j.jbc.2021.101178