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Interdependence of neural network dysfunction and microglial alterations in Alzheimer’s disease-related models

Nonconvulsive epileptiform activity and microglial alterations have been detected in people with Alzheimer’s disease (AD) and related mouse models. However, the relationship between these abnormalities remains to be elucidated. We suppressed epileptiform activity by treatment with the antiepileptic...

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Detalles Bibliográficos
Autores principales: Das, Melanie, Mao, Wenjie, Shao, Eric, Tamhankar, Soniya, Yu, Gui-Qiu, Yu, Xinxing, Ho, Kaitlyn, Wang, Xin, Wang, Jiaming, Mucke, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561005/
https://www.ncbi.nlm.nih.gov/pubmed/34755090
http://dx.doi.org/10.1016/j.isci.2021.103245