Prostaglandin E(2) directly inhibits the conversion of inducible regulatory T cells through EP2 and EP4 receptors via antagonizing TGF‐β signalling

Regulatory T (Treg) cells are essential for control of inflammatory processes by suppressing effector T‐cell functions. The actions of PGE(2) on the development and function of Treg cells, particularly under inflammatory conditions, are debated. In this study, we employed pharmacological and genetic...

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Detalles Bibliográficos
Autores principales: Goepp, Marie, Crittenden, Siobhan, Zhou, You, Rossi, Adriano G, Narumiya, Shuh, Yao, Chengcan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561111/
https://www.ncbi.nlm.nih.gov/pubmed/34529833
http://dx.doi.org/10.1111/imm.13417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561111/
https://www.ncbi.nlm.nih.gov/pubmed/34529833
http://dx.doi.org/10.1111/imm.13417

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