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Prostaglandin E(2) directly inhibits the conversion of inducible regulatory T cells through EP2 and EP4 receptors via antagonizing TGF‐β signalling
Regulatory T (Treg) cells are essential for control of inflammatory processes by suppressing effector T‐cell functions. The actions of PGE(2) on the development and function of Treg cells, particularly under inflammatory conditions, are debated. In this study, we employed pharmacological and genetic...
Autores principales: | Goepp, Marie, Crittenden, Siobhan, Zhou, You, Rossi, Adriano G, Narumiya, Shuh, Yao, Chengcan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561111/ https://www.ncbi.nlm.nih.gov/pubmed/34529833 http://dx.doi.org/10.1111/imm.13417 |
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