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Memory CD8(+) T cells exhibit tissue imprinting and non‐stable exposure‐dependent reactivation characteristics following blood‐stage Plasmodium berghei ANKA infections

Experimental cerebral malaria (ECM) is a severe complication of Plasmodium berghei ANKA (PbA) infection in mice, characterized by CD8(+) T‐cell accumulation within the brain. Whilst the dynamics of CD8(+) T‐cell activation and migration during extant primary PbA infection have been extensively resea...

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Detalles Bibliográficos
Autores principales: Shaw, Tovah N., Haley, Michael J., Dookie, Rebecca S., Godfrey, Jenna J., Cheeseman, Antonn J., Strangward, Patrick, Zeef, Leo A. H., Villegas‐Mendez, Ana, Couper, Kevin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561116/
https://www.ncbi.nlm.nih.gov/pubmed/34407221
http://dx.doi.org/10.1111/imm.13405