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Pre-existing infant antibody-dependent cellular cytotoxicity associates with reduced HIV-1 acquisition and lower morbidity

In humans, pre-existing anti-HIV-1 neutralizing antibodies (nAbs) have not been associated with decreased HIV-1 acquisition. Here, we evaluate antibody-dependent cellular cytotoxicity (ADCC) present in pre-transmission infant and maternal plasma and breast milk (BM) against the contemporaneous mater...

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Detalles Bibliográficos
Autores principales: Thomas, Allison S., Moreau, Yvetane, Jiang, Wenqing, Isaac, John E., Ewing, Alexander, White, Laura F., Kourtis, Athena P., Sagar, Manish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561235/
https://www.ncbi.nlm.nih.gov/pubmed/34755132
http://dx.doi.org/10.1016/j.xcrm.2021.100412