Intravenous iron preparations transiently generate non-transferrin-bound iron from two proposed pathways

Intravenous iron-carbohydrate complex preparations (IVIP) are noninterchangeable pro-drugs: their pharmacokinetics (PK) varies determined by semi-crystalline iron core and carbohydrate shell structures, influences pharmacodynamics (PD) and thus efficacy and safety. Examining PK/PD relationships of t...

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Detalles Bibliográficos
Autores principales: Garbowski, Maciej W., Bansal, Sukhvinder, Porter, John B., Mori, Claudio, Burckhardt, Susanna, Hider, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561294/
https://www.ncbi.nlm.nih.gov/pubmed/33054113
http://dx.doi.org/10.3324/haematol.2020.250803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561294/
https://www.ncbi.nlm.nih.gov/pubmed/33054113
http://dx.doi.org/10.3324/haematol.2020.250803

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