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Human IFIT3 Protein Induces Interferon Signaling and Inhibits Adenovirus Immediate Early Gene Expression

Interferons (IFNs) are one of the hallmarks of host antiviral immunity. IFNs exert their antiviral activities through the induction of IFN-stimulated genes (ISGs) and antiviral proteins; however, the mechanism by which ISGs inhibit adenovirus (Ad) replication is not clearly understood. IFNs repress...

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Detalles Bibliográficos
Autores principales: Chikhalya, Aniska, Dittmann, Meike, Zheng, Yueting, Sohn, Sook-Young, Rice, Charles M., Hearing, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561380/
https://www.ncbi.nlm.nih.gov/pubmed/34724821
http://dx.doi.org/10.1128/mBio.02829-21