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SepA Enhances Shigella Invasion of Epithelial Cells by Degrading Alpha-1 Antitrypsin and Producing a Neutrophil Chemoattractant
Shigella spp. are highly adapted pathogens that cause bacillary dysentery in human and nonhuman primates. An unusual feature of Shigella pathogenesis is that this organism invades the colonic epithelia from the basolateral pole. Therefore, it has evolved the ability to disrupt the intestinal epithel...
Autores principales: | Meza-Segura, Mario, Birtley, James R., Maldonado-Contreras, Ana, Mueller, Christian, Simin, Karl J., Stern, Lawrence J., McCormick, Beth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561385/ https://www.ncbi.nlm.nih.gov/pubmed/34724811 http://dx.doi.org/10.1128/mBio.02833-21 |
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