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High-Throughput Mutagenesis and Cross-Complementation Experiments Reveal Substrate Preference and Critical Residues of the Capsule Transporters in Streptococcus pneumoniae

MOP (Multidrug/Oligosaccharidyl-lipid/Polysaccharide) family transporters are found in almost all life forms. They are responsible for transporting lipid-linked precursors across the cell membrane to support the synthesis of various glycoconjugates. While significant progress has been made in elucid...

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Detalles Bibliográficos
Autores principales: Chua, Wan-Zhen, Maiwald, Matthias, Chew, Kean Lee, Lin, Raymond Tzer-Pin, Zheng, Sanduo, Sham, Lok-To
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561386/
https://www.ncbi.nlm.nih.gov/pubmed/34724815
http://dx.doi.org/10.1128/mBio.02615-21