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New Mechanistic Insights into Purine Biosynthesis with Second Messenger c-di-AMP in Relation to Biofilm-Related Persistent Methicillin-Resistant Staphylococcus aureus Infections

Persistent methicillin-resistant Staphylococcus aureus (MRSA) endovascular infections represent a significant clinically challenging subset of invasive, life-threatening S. aureus infections. We have recently demonstrated that purine biosynthesis plays an important role in such persistent infections...

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Detalles Bibliográficos
Autores principales: Li, Liang, Li, Yi, Zhu, Fengli, Cheung, Ambrose L., Wang, Genzhu, Bai, Guangchun, Proctor, Richard A., Yeaman, Michael R., Bayer, Arnold S., Xiong, Yan Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561390/
https://www.ncbi.nlm.nih.gov/pubmed/34724823
http://dx.doi.org/10.1128/mBio.02081-21