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New Mechanistic Insights into Purine Biosynthesis with Second Messenger c-di-AMP in Relation to Biofilm-Related Persistent Methicillin-Resistant Staphylococcus aureus Infections
Persistent methicillin-resistant Staphylococcus aureus (MRSA) endovascular infections represent a significant clinically challenging subset of invasive, life-threatening S. aureus infections. We have recently demonstrated that purine biosynthesis plays an important role in such persistent infections...
Autores principales: | Li, Liang, Li, Yi, Zhu, Fengli, Cheung, Ambrose L., Wang, Genzhu, Bai, Guangchun, Proctor, Richard A., Yeaman, Michael R., Bayer, Arnold S., Xiong, Yan Q. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561390/ https://www.ncbi.nlm.nih.gov/pubmed/34724823 http://dx.doi.org/10.1128/mBio.02081-21 |
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