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Minor Alterations in Core Promoter Element Positioning Reveal Functional Plasticity of a Bacterial Transcription Factor

IscR is a global transcription factor that regulates Fe-S cluster homeostasis and other functions in Escherichia coli by either activating or repressing transcription. While the interaction of IscR with its DNA sites has been studied, less is known about the mechanism of IscR regulation of transcrip...

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Detalles Bibliográficos
Autores principales: Chowdhury, Wamiah P., Satyshur, Kenneth A., Keck, James L., Kiley, Patricia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561392/
https://www.ncbi.nlm.nih.gov/pubmed/34724814
http://dx.doi.org/10.1128/mBio.02753-21