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Integrative analysis of genomic and epigenomic data reveal underlying superenhancer-mediated microRNA regulatory network for human bone mineral density

Bone mineral density (BMD) is a highly heritable complex trait and is a key indicator for diagnosis and treatment for osteoporosis. In the last decade, numerous susceptibility loci for BMD and fracture have been identified by genome-wide association studies (GWAS); however, fine mapping of these loc...

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Detalles Bibliográficos
Autores principales: Bai, Wei-Yang, Xia, Jiang-Wei, Rong, Xiao-Li, Cong, Pei-Kuan, Khederzadeh, Saber, Zheng, Hou-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561425/
https://www.ncbi.nlm.nih.gov/pubmed/34230965
http://dx.doi.org/10.1093/hmg/ddab181