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Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 increases cellular proliferation and colony formation capacity in lung cancer via activation of E2F transcription factor 1

Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (PLOD1) is an enzyme that catalyzes the hydroxylation of lysyl residues in collagen-like peptides, and is responsible for the stability of intermolecular crosslinks. High PLOD1 mRNA levels have been determined to be prognostically significant in num...

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Detalles Bibliográficos
Autores principales: Li, Baijun, Yang, Hao, Shen, Bin, Huang, Jianwei, Qin, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561618/
https://www.ncbi.nlm.nih.gov/pubmed/34733369
http://dx.doi.org/10.3892/ol.2021.13112