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Metformin inhibits the proliferation of canine mammary gland tumor cells through the AMPK/AKT/mTOR signaling pathway in vitro

As an anti-diabetic drug, metformin has been demonstrated to exhibit antitumor effects. However, the mechanisms involved in decreasing tumor formation, including canine mammary gland tumors (CMGTs), are not well elucidated. The aim of the present study was to evaluate the ability of metformin to ind...

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Detalles Bibliográficos
Autores principales: Fan, Yuying, Ren, Xiaoli, Wang, Yingxue, Xu, Enshuang, Wang, Shuang, Ge, Ruidong, Liu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561621/
https://www.ncbi.nlm.nih.gov/pubmed/34733370
http://dx.doi.org/10.3892/ol.2021.13113