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Ablation of mitochondrial DNA results in widespread remodeling of the mitochondrial complexome

So‐called ρ0 cells lack mitochondrial DNA and are therefore incapable of aerobic ATP synthesis. How cells adapt to survive ablation of oxidative phosphorylation remains poorly understood. Complexome profiling analysis of ρ0 cells covered 1,002 mitochondrial proteins and revealed changes in abundance...

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Detalles Bibliográficos
Autores principales: Guerrero‐Castillo, Sergio, van Strien, Joeri, Brandt, Ulrich, Arnold, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561636/
https://www.ncbi.nlm.nih.gov/pubmed/34542926
http://dx.doi.org/10.15252/embj.2021108648