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Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses

RNA viruses induce the formation of subcellular organelles that provide microenvironments conducive to their replication. Here we show that replication factories of rotaviruses represent protein‐RNA condensates that are formed via liquid–liquid phase separation of the viroplasm‐forming proteins NSP5...

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Detalles Bibliográficos
Autores principales: Geiger, Florian, Acker, Julia, Papa, Guido, Wang, Xinyu, Arter, William E, Saar, Kadi L, Erkamp, Nadia A, Qi, Runzhang, Bravo, Jack PK, Strauss, Sebastian, Krainer, Georg, Burrone, Oscar R, Jungmann, Ralf, Knowles, Tuomas PJ, Engelke, Hanna, Borodavka, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561643/
https://www.ncbi.nlm.nih.gov/pubmed/34524703
http://dx.doi.org/10.15252/embj.2021107711