Cytochrome P450 and Flavin-containing Monooxygenase Families: Age-Dependent Differences in Expression and Functional Activity

BACKGROUND: Age-dependent differences in pharmacokinetics exist for metabolically cleared medications. Differential contributions in the cytochrome P450 3A (CYP3A), CYP2C, and flavin-containing monooxygenases (FMO) families play an important role in the metabolic clearance of a large number of drugs...

Descripción completa

Detalles Bibliográficos
Autores principales: Zane, Nicole R., Chen, Yao, Wang, Michael Zhuo, Thakker, Dhiren R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561720/
https://www.ncbi.nlm.nih.gov/pubmed/28922349
http://dx.doi.org/10.1038/pr.2017.226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561720/
https://www.ncbi.nlm.nih.gov/pubmed/28922349
http://dx.doi.org/10.1038/pr.2017.226

Ejemplares similares