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Placental extract suppresses the formation of fibrotic deposits by tumor necrosis factor alpha and transforming growth factor beta-induced epithelial–mesenchymal transition in ARPE-19 cells

OBJECTIVE: Epithelial–mesenchymal transition (EMT) is involved in the development of proliferative vitreoretinopathy (PVR) and subsequent fibrosis. Previously, we demonstrated that placental extract ameliorates fibrosis in a mouse model of non-alcoholic steatohepatitis. In this study, we evaluated w...

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Detalles Bibliográficos
Autores principales: Igarashi, Kyoko, Sugimoto, Koji, Hirano, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561846/
https://www.ncbi.nlm.nih.gov/pubmed/34727968
http://dx.doi.org/10.1186/s13104-021-05824-0