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Regulation of the p75 neurotrophin receptor attenuates neuroinflammation and stimulates hippocampal neurogenesis in experimental Streptococcus pneumoniae meningitis

BACKGROUND: Streptococcus pneumoniae meningitis is a destructive central nervous system (CNS) infection with acute and long-term neurological disorders. Previous studies suggest that p75NTR signaling influences cell survival, apoptosis, and proliferation in brain-injured conditions. However, the rol...

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Detalles Bibliográficos
Autores principales: Zhang, Dandan, Zhao, Shengnan, Zhang, Zhijie, Xu, Danfeng, Lian, Di, Wu, Jing, He, Dake, Sun, Kun, Li, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561879/
https://www.ncbi.nlm.nih.gov/pubmed/34727939
http://dx.doi.org/10.1186/s12974-021-02294-w