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Regulation of the p75 neurotrophin receptor attenuates neuroinflammation and stimulates hippocampal neurogenesis in experimental Streptococcus pneumoniae meningitis
BACKGROUND: Streptococcus pneumoniae meningitis is a destructive central nervous system (CNS) infection with acute and long-term neurological disorders. Previous studies suggest that p75NTR signaling influences cell survival, apoptosis, and proliferation in brain-injured conditions. However, the rol...
Autores principales: | Zhang, Dandan, Zhao, Shengnan, Zhang, Zhijie, Xu, Danfeng, Lian, Di, Wu, Jing, He, Dake, Sun, Kun, Li, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561879/ https://www.ncbi.nlm.nih.gov/pubmed/34727939 http://dx.doi.org/10.1186/s12974-021-02294-w |
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