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Self-extracellular RNA promotes pro-inflammatory response of astrocytes to exogenous and endogenous danger signals

OBJECTIVE: Astrocytes participate in the local innate immune response of the central nervous system. In response to stress such as ischemia, activated cells release endogenous factors known as damage-associated molecular patterns (DAMPs). Self-extracellular RNA (eRNA) is such a ubiquitous alarm sign...

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Detalles Bibliográficos
Autores principales: Fischer, Silvia, Nasyrov, Emil, Brosien, Monika, Preissner, Klaus T., Marti, Hugo H., Kunze, Reiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561902/
https://www.ncbi.nlm.nih.gov/pubmed/34727934
http://dx.doi.org/10.1186/s12974-021-02286-w