Modification of improved-genome editing via oviductal nucleic acids delivery (i-GONAD)-mediated knock-in in rats

BACKGROUND: Improved genome-editing via oviductal nucleic acids delivery (i-GONAD) is a new technology that facilitates in situ genome-editing of mammalian zygotes exiting the oviductal lumen. The i-GONAD technology has been developed for use in mice, rats, and hamsters; however, oligonucleotide (OD...

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Detalles Bibliográficos
Autores principales: Aoshima, Takuya, Kobayashi, Yukari, Takagi, Hisayoshi, Iijima, Kenta, Sato, Masahiro, Takabayashi, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561937/
https://www.ncbi.nlm.nih.gov/pubmed/34724929
http://dx.doi.org/10.1186/s12896-021-00723-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561937/
https://www.ncbi.nlm.nih.gov/pubmed/34724929
http://dx.doi.org/10.1186/s12896-021-00723-5

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