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Modification of improved-genome editing via oviductal nucleic acids delivery (i-GONAD)-mediated knock-in in rats

BACKGROUND: Improved genome-editing via oviductal nucleic acids delivery (i-GONAD) is a new technology that facilitates in situ genome-editing of mammalian zygotes exiting the oviductal lumen. The i-GONAD technology has been developed for use in mice, rats, and hamsters; however, oligonucleotide (OD...

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Detalles Bibliográficos
Autores principales:	Aoshima, Takuya, Kobayashi, Yukari, Takagi, Hisayoshi, Iijima, Kenta, Sato, Masahiro, Takabayashi, Shuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561937/ https://www.ncbi.nlm.nih.gov/pubmed/34724929 http://dx.doi.org/10.1186/s12896-021-00723-5

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