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Cancer-associated fibroblast heterogeneity is associated with organ-specific metastasis in pancreatic ductal adenocarcinoma

BACKGROUND: Metastasis occurs in the majority of pancreatic ductal adenocarcinoma (PDAC) patients at diagnosis or following resection. Patients with liver metastasis and those with lung metastasis have significantly different prognosis. Here, we sought to understand how cancer-associated fibroblasts...

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Detalles Bibliográficos
Autores principales: Pan, Xingyi, Zhou, Jiaojiao, Xiao, Qian, Fujiwara, Kenji, Zhang, Mengwen, Mo, Guanglan, Gong, Wei, Zheng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561960/
https://www.ncbi.nlm.nih.gov/pubmed/34727952
http://dx.doi.org/10.1186/s13045-021-01203-1