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Instant activation of TRP channels by NH(4)(+) promotes neuronal bursting and glutamate spikes in CA1 neurons
Ammonia ([Formula: see text]) is a by-product of cell metabolism and may elicit subcellular effects with specific physiological responses. Chronic effects have been implicated in several neurological diseases and attributed to persistent elevation in blood ammonia levels transferred to the brain. In...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562246/ https://www.ncbi.nlm.nih.gov/pubmed/34746817 http://dx.doi.org/10.1016/j.crphys.2020.05.002 |