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Instant activation of TRP channels by NH(4)(+) promotes neuronal bursting and glutamate spikes in CA1 neurons

Ammonia ([Formula: see text]) is a by-product of cell metabolism and may elicit subcellular effects with specific physiological responses. Chronic effects have been implicated in several neurological diseases and attributed to persistent elevation in blood ammonia levels transferred to the brain. In...

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Detalles Bibliográficos
Autores principales: Balakrishnan, Saju, Mironov, Sergej L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562246/
https://www.ncbi.nlm.nih.gov/pubmed/34746817
http://dx.doi.org/10.1016/j.crphys.2020.05.002