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Design of a chitosan-based nano vaccine against epsilon toxin of Clostridium perfringens type D and evaluation of its immunogenicity in BALB/c mice

BACKGROUND AND PURPOSE: Clostridium perfringens is an anaerobic, spore-forming, and pathogenic bacterium that causes intestinal diseases in humans and animals. In these cases, therapeutic intervention is challenging; because the disease progresses much rapidly. This bacterium can produce 5 main toxi...

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Detalles Bibliográficos
Autores principales: Poorhassan, Farnaz, Nemati, Fahimeh, Saffarian, Parvaneh, Mirhosseini, Seyed Ali, Motamedi, Mohammad Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562408/
https://www.ncbi.nlm.nih.gov/pubmed/34760006
http://dx.doi.org/10.4103/1735-5362.327504