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Attenuating effects of allantoin on oxidative stress in a mouse model of nonalcoholic steatohepatitis: role of SIRT1/Nrf2 pathway

BACKGROUND AND PURPOSE: Nonalcoholic steatohepatitis (NASH) is considered a common and serious liver disease, which develops into cirrhosis, fibrosis, and even hepatocellular carcinoma. Oxidative stress is identified as an important factor in the induction and promotion of NASH. Allantoin is a natur...

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Detalles Bibliográficos
Autores principales: Hamidi-zad, Zeinab, Moslehi, Azam, Rastegarpanah, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562413/
https://www.ncbi.nlm.nih.gov/pubmed/34760013
http://dx.doi.org/10.4103/1735-5362.327511