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Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder cancer
BACKGROUND: Immune checkpoint blockade (ICB) induces durable response in approximately 20% of patients with advanced bladder urothelial cancer (aUC). Over 50% of aUCs harbor genomic alterations along the phosphoinositide 3-kinase (PI3K) pathway. The goal of this project was to determine the synergis...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562536/ https://www.ncbi.nlm.nih.gov/pubmed/34725212 http://dx.doi.org/10.1136/jitc-2021-002917 |