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Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits

Psychological and social factors are known to influence blood pressure (BP) and risk of hypertension and associated cardiovascular diseases. To identify novel BP loci, we carried out genome-wide association meta-analyses of systolic, diastolic, pulse, and mean arterial BP, taking into account the in...

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Detalles Bibliográficos
Autores principales: Sun, Daokun, Richard, Melissa A., Musani, Solomon K., Sung, Yun Ju, Winkler, Thomas W., Schwander, Karen, Chai, Jin Fang, Guo, Xiuqing, Kilpeläinen, Tuomas O., Vojinovic, Dina, Aschard, Hugues, Bartz, Traci M., Bielak, Lawrence F., Brown, Michael R., Chitrala, Kumaraswamy, Hartwig, Fernando P., Horimoto, Andrea R.V.R., Liu, Yongmei, Manning, Alisa K., Noordam, Raymond, Smith, Albert V., Harris, Sarah E., Kühnel, Brigitte, Lyytikäinen, Leo-Pekka, Nolte, Ilja M., Rauramaa, Rainer, van der Most, Peter J., Wang, Rujia, Ware, Erin B., Weiss, Stefan, Wen, Wanqing, Yanek, Lisa R., Arking, Dan E., Arnett, Donna K., Barac, Ana, Boerwinkle, Eric, Broeckel, Ulrich, Chakravarti, Aravinda, Chen, Yii-Der Ida, Cupples, L. Adrienne, Davigulus, Martha L., de las Fuentes, Lisa, de Mutsert, Renée, de Vries, Paul S., Delaney, Joseph A.C., Diez Roux, Ana V., Dörr, Marcus, Faul, Jessica D., Fretts, Amanda M., Gallo, Linda C., Grabe, Hans Jörgen, Gu, C. Charles, Harris, Tamara B., Hartman, Catharina C.A., Heikkinen, Sami, Ikram, M. Arfan, Isasi, Carmen, Johnson, W. Craig, Jonas, Jost Bruno, Kaplan, Robert C., Komulainen, Pirjo, Krieger, Jose E., Levy, Daniel, Liu, Jianjun, Lohman, Kurt, Luik, Annemarie I., Martin, Lisa W., Meitinger, Thomas, Milaneschi, Yuri, O’Connell, Jeff R., Palmas, Walter R., Peters, Annette, Peyser, Patricia A., Pulkki-Råback, Laura, Raffel, Leslie J., Reiner, Alex P., Rice, Kenneth, Robinson, Jennifer G., Rosendaal, Frits R., Schmidt, Carsten Oliver, Schreiner, Pamela J., Schwettmann, Lars, Shikany, James M., Shu, Xiao-ou, Sidney, Stephen, Sims, Mario, Smith, Jennifer A., Sotoodehnia, Nona, Strauch, Konstantin, Tai, E. Shyong, Taylor, Kent D., Uitterlinden, André G., van Duijn, Cornelia M., Waldenberger, Melanie, Wee, Hwee-Lin, Wei, Wen-Bin, Wilson, Gregory, Xuan, Deng, Yao, Jie, Zeng, Donglin, Zhao, Wei, Zhu, Xiaofeng, Zonderman, Alan B., Becker, Diane M., Deary, Ian J., Gieger, Christian, Lakka, Timo A., Lehtimäki, Terho, North, Kari E., Oldehinkel, Albertine J., Penninx, Brenda W.J.H., Snieder, Harold, Wang, Ya-Xing, Weir, David R., Zheng, Wei, Evans, Michele K., Gauderman, W. James, Gudnason, Vilmundur, Horta, Bernardo L., Liu, Ching-Ti, Mook-Kanamori, Dennis O., Morrison, Alanna C., Pereira, Alexandre C., Psaty, Bruce M., Amin, Najaf, Fox, Ervin R., Kooperberg, Charles, Sim, Xueling, Bierut, Laura, Rotter, Jerome I., Kardia, Sharon L.R., Franceschini, Nora, Rao, Dabeeru C., Fornage, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562625/
https://www.ncbi.nlm.nih.gov/pubmed/34734193
http://dx.doi.org/10.1016/j.xhgg.2020.100013