Michaelis-like complex of SARS-CoV-2 main protease visualized by room-temperature X-ray crystallography

SARS-CoV-2 emerged at the end of 2019 to cause an unprecedented pandemic of the deadly respiratory disease COVID-19 that continues to date. The viral main protease (M(pro)) is essential for SARS-CoV-2 replication and is therefore an important drug target. Understanding the catalytic mechanism of M(p...

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Detalles Bibliográficos
Autores principales: Kneller, Daniel W., Zhang, Qiu, Coates, Leighton, Louis, John M., Kovalevsky, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562657/
https://www.ncbi.nlm.nih.gov/pubmed/34804549
http://dx.doi.org/10.1107/S2052252521010113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562657/
https://www.ncbi.nlm.nih.gov/pubmed/34804549
http://dx.doi.org/10.1107/S2052252521010113

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