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Michaelis-like complex of SARS-CoV-2 main protease visualized by room-temperature X-ray crystallography
SARS-CoV-2 emerged at the end of 2019 to cause an unprecedented pandemic of the deadly respiratory disease COVID-19 that continues to date. The viral main protease (M(pro)) is essential for SARS-CoV-2 replication and is therefore an important drug target. Understanding the catalytic mechanism of M(p...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562657/ https://www.ncbi.nlm.nih.gov/pubmed/34804549 http://dx.doi.org/10.1107/S2052252521010113 |