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Perfluoroalkyl Carboxylic Acids Interact with the Human Bile Acid Transporter NTCP

Na(+)/taurocholate cotransporting polypeptide (NTCP) is important for the enterohepatic circulation of bile acids, which has been suggested to contribute to the long serum elimination half-lives of perfluoroalkyl substances in humans. We demonstrated that some perfluoroalkyl sulfonates are transport...

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Detalles Bibliográficos
Autores principales: Ruggiero, Melissa J., Miller, Haley, Idowu, Jessica Y., Zitzow, Jeremiah D., Chang, Shu-Ching, Hagenbuch, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562773/
https://www.ncbi.nlm.nih.gov/pubmed/34738093
http://dx.doi.org/10.3390/livers1040017