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An open, non-randomised, phase 1/2 trial on the safety, tolerability, and immunogenicity of single-dose vaccine “Sputnik Light” for prevention of coronavirus infection in healthy adults

BACKGROUND: While the world is experiencing another wave of COVID-19 pandemic, global vaccination program is hampered by an evident shortage in the supply of licensed vaccines. In an effort to satisfy vaccine demands we developed a new single-dose vaccine based on recombinant adenovirus type 26 (rAd...

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Detalles Bibliográficos
Autores principales: Tukhvatulin, Amir I., Dolzhikova, Inna V., Shcheblyakov, Dmitry V., Zubkova, Olga V., Dzharullaeva, Alina S., Kovyrshina, Anna V., Lubenets, Nadezhda L., Grousova, Daria M., Erokhova, Alina S., Botikov, Andrei G., Izhaeva, Fatima M., Popova, Olga, Ozharovskaia, Tatiana A., Esmagambetov, Ilias B., Favorskaya, Irina A., Zrelkin, Denis I., Voronina, Daria V., Shcherbinin, Dmitry N., Semikhin, Alexander S., Simakova, Yana V., Tokarskaya, Elizaveta A., Shmarov, Maksim M., Nikitenko, Natalia A., Gushchin, Vladimir A., Smolyarchuk, Elena A., Zubkova, Tatiana G., Zakharov, Konstantin A., Vasilyuk, Vasiliy B., Borisevich, Sergei V., Naroditsky, Boris S., Logunov, Denis Y., Gintsburg, Alexander L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562788/
https://www.ncbi.nlm.nih.gov/pubmed/34746910
http://dx.doi.org/10.1016/j.lanepe.2021.100241