Cargando…
Slipknotted and unknotted monovalent cation-proton antiporters evolved from a common ancestor
While the slipknot topology in proteins has been known for over a decade, its evolutionary origin is still a mystery. We have identified a previously overlooked slipknot motif in a family of two-domain membrane transporters. Moreover, we found that these proteins are homologous to several families o...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562792/ https://www.ncbi.nlm.nih.gov/pubmed/34648493 http://dx.doi.org/10.1371/journal.pcbi.1009502 |