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Mining the Protein Data Bank to improve prediction of changes in protein-protein binding
Predicting the effect of mutations on protein-protein interactions is important for relating structure to function, as well as for in silico affinity maturation. The effect of mutations on protein-protein binding energy (ΔΔG) can be predicted by a variety of atomic simulation methods involving full...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562805/ https://www.ncbi.nlm.nih.gov/pubmed/34727109 http://dx.doi.org/10.1371/journal.pone.0257614 |