Tyrosine phosphorylation of S1PR1 leads to chaperone BiP-mediated import to the endoplasmic reticulum

Cell surface G protein–coupled receptors (GPCRs), upon agonist binding, undergo serine–threonine phosphorylation, leading to either receptor recycling or degradation. Here, we show a new fate of GPCRs, exemplified by ER retention of sphingosine-1-phosphate receptor 1 (S1PR1). We show that S1P phosph...

Descripción completa

Detalles Bibliográficos
Autores principales: Anwar, Mumtaz, Amin, Md Ruhul, Balaji Ragunathrao, Vijay Avin, Matsche, Jacob, Karginov, Andrei, Minshall, Richard D., Mo, Gary C.H., Komarova, Yulia, Mehta, Dolly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562845/
https://www.ncbi.nlm.nih.gov/pubmed/34652421
http://dx.doi.org/10.1083/jcb.202006021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562845/
https://www.ncbi.nlm.nih.gov/pubmed/34652421
http://dx.doi.org/10.1083/jcb.202006021

Ejemplares similares