iASPP contributes to cell cortex rigidity, mitotic cell rounding, and spindle positioning

iASPP is a protein mostly known as an inhibitor of p53 pro-apoptotic activity and a predicted regulatory subunit of the PP1 phosphatase, which is often overexpressed in tumors. We report that iASPP associates with the microtubule plus-end binding protein EB1, a central regulator of microtubule dynam...

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Detalles Bibliográficos
Autores principales: Mangon, Aurélie, Salaün, Danièle, Bouali, Mohamed Lala, Kuzmić, Mira, Quitard, Sabine, Thuault, Sylvie, Isnardon, Daniel, Audebert, Stéphane, Puech, Pierre-Henri, Verdier-Pinard, Pascal, Badache, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562848/
https://www.ncbi.nlm.nih.gov/pubmed/34705028
http://dx.doi.org/10.1083/jcb.202012002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562848/
https://www.ncbi.nlm.nih.gov/pubmed/34705028
http://dx.doi.org/10.1083/jcb.202012002

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