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Efficacy and Safety of a 3-Antigen (Pre-S1/Pre-S2/S) Hepatitis B Vaccine: Results of a Phase 3 Randomized Clinical Trial in the Russian Federation

BACKGROUND: This study compares the immunogenicity and safety of a 3-antigen (S/pre-S1/pre-S2) hepatitis B (HepB) vaccine (3AV), to a single antigen vaccine (1AV) in adults to support the registration of 3AV in Russia. METHODS: We conducted a randomized, double-blind, comparative study of 3-dose reg...

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Detalles Bibliográficos
Autores principales: Esaulenko, Elena V, Yakovlev, Aleksey A, Volkov, Genady A, Sukhoruk, Anastasia A, Surkov, Kirill G, Kruglyakov, Peter V, Diaz-Mitoma, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563202/
https://www.ncbi.nlm.nih.gov/pubmed/33119068
http://dx.doi.org/10.1093/cid/ciaa1649