Allogeneic CAR Invariant Natural Killer T Cells Exert Potent Antitumor Effects through Host CD8 T-Cell Cross-Priming

PURPOSE: The development of allogeneic chimeric antigen receptor (CAR) T-cell therapies for off-the-shelf use is a major goal that faces two main immunologic challenges, namely the risk of graft-versus-host disease (GvHD) induction by the transferred cells and the rejection by the host immune system...

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Detalles Bibliográficos
Autores principales: Simonetta, Federico, Lohmeyer, Juliane K., Hirai, Toshihito, Maas-Bauer, Kristina, Alvarez, Maite, Wenokur, Arielle S., Baker, Jeanette, Aalipour, Amin, Ji, Xuhuai, Haile, Samuel, Mackall, Crystal L., Negrin, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563377/
https://www.ncbi.nlm.nih.gov/pubmed/34376537
http://dx.doi.org/10.1158/1078-0432.CCR-21-1329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563377/
https://www.ncbi.nlm.nih.gov/pubmed/34376537
http://dx.doi.org/10.1158/1078-0432.CCR-21-1329

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