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A bioinspired and chemically defined alternative to dimethyl sulfoxide for the cryopreservation of human hematopoietic stem cells

The cryopreservation of hematopoietic cells using dimethyl sulfoxide (DMSO) and serum is a common procedure used in transplantation. However, DMSO has clinical and biological side effects due to its toxicity, and serum introduces variation and safety risks. Inspired by natural antifreeze proteins, a...

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Detalles Bibliográficos
Autores principales: Gilfanova, Renata, Callegari, Andrea, Childs, Adam, Yang, Gaomai, Luarca, Miranda, Gutierrez, Alan G., Medina, Karla I., Mai, Justin, Hui, Alvin, Kline, Mark, Wei, Xiaoxi, Norris, Philip J., Muench, Marcus O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563414/
https://www.ncbi.nlm.nih.gov/pubmed/34155359
http://dx.doi.org/10.1038/s41409-021-01368-w