Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer

Oxidative phosphorylation (OXPHOS) is an active metabolic pathway in many cancers. RNA from pretreatment biopsies from patients with triple-negative breast cancer (TNBC) who received neoadjuvant chemotherapy demonstrated that the top canonical pathway associated with worse outcome was higher express...

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Detalles Bibliográficos
Autores principales: Evans, Kurt W., Yuca, Erkan, Scott, Stephen S., Zhao, Ming, Paez Arango, Natalia, Cruz Pico, Christian X., Saridogan, Turcin, Shariati, Maryam, Class, Caleb A., Bristow, Christopher A., Vellano, Christopher P., Zheng, Xiaofeng, Gonzalez-Angulo, Ana Maria, Su, Xiaoping, Tapia, Coya, Chen, Ken, Akcakanat, Argun, Lim, Bora, Tripathy, Debu, Yap, Timothy A., Francesco, Maria Emilia Di, Draetta, Giulio F., Jones, Philip, Heffernan, Timothy P., Marszalek, Joseph R., Meric-Bernstam, Funda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Translational Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563442/
https://www.ncbi.nlm.nih.gov/pubmed/34518211
http://dx.doi.org/10.1158/0008-5472.CAN-20-3242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563442/
https://www.ncbi.nlm.nih.gov/pubmed/34518211
http://dx.doi.org/10.1158/0008-5472.CAN-20-3242

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