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A systematic review of neuropsychiatric and cognitive assessments used in clinical trials for amyotrophic lateral sclerosis

BACKGROUND: Up to 50% of people with amyotrophic lateral sclerosis (ALS) experience cognitive dysfunction, whilst depression and anxiety are reported in up to 44% and 33%, respectively. These symptoms impact on quality of life, and are associated with a poorer prognosis. Historically, outcomes in cl...

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Detalles Bibliográficos
Autores principales: Beswick, Emily, Park, Emily, Wong, Charis, Mehta, Arpan R., Dakin, Rachel, Chandran, Siddharthan, Newton, Judith, Carson, Alan, Abrahams, Sharon, Pal, Suvankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563523/
https://www.ncbi.nlm.nih.gov/pubmed/32910255
http://dx.doi.org/10.1007/s00415-020-10203-z