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Characterisation of Ppy-lineage cells clarifies the functional heterogeneity of pancreatic beta cells in mice

AIMS/HYPOTHESIS: Pancreatic polypeptide (PP) cells, which secrete PP (encoded by the Ppy gene), are a minor population of pancreatic endocrine cells. Although it has been reported that the loss of beta cell identity might be associated with beta-to-PP cell-fate conversion, at present, little is know...

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Detalles Bibliográficos
Autores principales: Fukaishi, Takahiro, Nakagawa, Yuko, Fukunaka, Ayako, Sato, Takashi, Hara, Akemi, Nakao, Keiko, Saito, Michiko, Kohno, Kenji, Miyatsuka, Takeshi, Tamaki, Motoyuki, Matsuhisa, Munehide, Matsuoka, Taka-aki, Yamada, Tetsuya, Watada, Hirotaka, Fujitani, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563568/
https://www.ncbi.nlm.nih.gov/pubmed/34498099
http://dx.doi.org/10.1007/s00125-021-05560-x