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Microinjection of pruritogens in NGF-sensitized human skin

Single intradermal injections of nerve growth factor (NGF) evoke prolonged but temporally distinct sensitization patterns to somatosensory stimuli. Focal administration of the non-histaminergic pruritogen cowhage but not histamine resulted in elevated itch at day 21 after NGF administration. Here, w...

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Detalles Bibliográficos
Autores principales: Solinski, Hans Jürgen, Rukwied, Roman, Schmelz, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563721/
https://www.ncbi.nlm.nih.gov/pubmed/34728705
http://dx.doi.org/10.1038/s41598-021-00935-x