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Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants

Accumulating mutations in the SARS-CoV-2 Spike (S) protein can increase the possibility of immune escape, challenging the present COVID-19 prophylaxis and clinical interventions. Here, 3 receptor binding domain (RBD) specific monoclonal antibodies (mAbs), 58G6, 510A5 and 13G9, with high neutralizing...

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Detalles Bibliográficos
Autores principales: Li, Tingting, Han, Xiaojian, Gu, Chenjian, Guo, Hangtian, Zhang, Huajun, Wang, Yingming, Hu, Chao, Wang, Kai, Liu, Fengjiang, Luo, Feiyang, Zhang, Yanan, Hu, Jie, Wang, Wang, Li, Shenglong, Hao, Yanan, Shen, Meiying, Huang, Jingjing, Long, Yingyi, Song, Shuyi, Wu, Ruixin, Mu, Song, Chen, Qian, Gao, Fengxia, Wang, Jianwei, Long, Shunhua, Li, Luo, Wu, Yang, Gao, Yan, Xu, Wei, Cai, Xia, Qu, Di, Zhang, Zherui, Zhang, Hongqing, Li, Na, Gao, Qingzhu, Zhang, Guiji, He, Changlong, Wang, Wei, Ji, Xiaoyun, Tang, Ni, Yuan, Zhenghong, Xie, Youhua, Yang, Haitao, Zhang, Bo, Huang, Ailong, Jin, Aishun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563728/
https://www.ncbi.nlm.nih.gov/pubmed/34728625
http://dx.doi.org/10.1038/s41467-021-26539-7